The brain is constantly active in sleep and wakefulness. Most of its activity is spontaneous, that is, it is not provoked by any external stimulus. This activity is key to our cognitive processes, and is highly structured.
There is a network in the brain, the so-called default mode network (DMN), that is actually more active when we are not doing anything than when we are engaged in cognitive activities.
Our key hypothesis is that the default mode network is also crucial for memory, because of its tight link to the hippocampus, the ‘hub’ of the memory network in the brain.
Thanks to an ERC Advanced Grant (approx. 2.5 million€) will use advanced optical imaging to observe memory replay globally in the brain, testing the hypothesis that the DMN is the glue that keeps the whole memory together.
If you are a specialist of imaging (VS/Ca2+/2P) or a computational person interested in a project with resting state networks, memory and computation, please contact Francesco Battaglia at email@example.com